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Obstetrics Gynecology 2020: Effect of metformin use on the risk and prognosis of ovarian cancer: an updated systematic review and meta-analysis -Min-zhen LU, The second clinical medical college

Min-zhen LU

Emerging evidences suggest that metformin has a potential antitumor effect both in vitro and in vivo. Increasing epidemiological studies indicate that diabetic patients receiving metformin therapy have lower incidences of cancer and have better survival rates. However, there are limited and inconsistent studies available about the effect of metformin therapy on ovarian cancer (OC). Thus, we conducted this meta-analysis to study the effect of metformin therapy on OC. Meanwhile, we systematically reviewed relevant studies to provide a framework for future research