Revista de Nutrição e Ciências Alimentares
Acesso livre

Abstrato

Effect of Saudi Propolis on Hepatitis Male Rats

Hassan Abd E, Elhendy R, Al-Yamani MAS and Sayrafi MA

This study was conducted to evaluate the benefits of the Saudi gum (propolis) by reduction of the toxic substances in rats that target the liver and affect its performance. The chemical components of propolis were identified. The study included 42 Albino male rat of a healthy weight ranged from 255-287 g, and they were divided into six equal groups. The first group was fed the standard diet (negative control group), while the other 35 rats were injected with carbon tetrachloride under the skin (1.5 ml/ kg) in order to infect them with acute hepatitis. After 24 h, the groups of infected rats were divided and the second group (positive control group) was also fed a standard meal, while the other groups infected which were the third, fourth, fifth and sixth were fed on a diet with access to a standard concentration of Saudi bee gum of 200, 300, 400 and 500 mg/kg, respectively, through the mouth for 4 consecutive weeks. The results showed that propolis contains 41 compounds and out of these 17 compounds have been identified. Volatile oil was in proportion of 20.37%, aliphatic acids in 16.87%, and esters in 15.48% and alcohols in 13.98%. The results showed a significant improvement in the biochemical parameters in hepatitis rats which were treated with propolis. Results also showed that propolis increased the activity of antioxidant enzymes in the liver of hepatitis rats treated with propolis. The study concluded that propolis plays an effective role in protecting the liver from damage and inflammation that can be caused by the components of antioxidation and inflammation.