Jornal de Desenvolvimento de Drogas
Acesso livre

Abstrato

Phytosomes: A Modernistic Approach for Novel Herbal Drug Delivery - Enhancing Bioavailability and Revealing Endless Frontier of Phytopharmaceuticals

Sudhir Kumar, Ashish Baldi, Dinesh Kumar Sharma

Phytopharmaceuticals are healing the world from millions and billions of years even though their clinical validation is questioned by virtue of their impediments like low lipid solubility, poor stability, large size moiety and needless metabolism in gut. Phytosome technology has emerged as committed and promising targeting novel drug delivery with improved efficacy, quality and target ability of active plant constituents. Novel herbal formulation techniques have assured the researchers to deliver the plant based secondary metabolites to their systemic targets. This review highlights the unique properties of phytophospholipid complex along with their application in the novel natural drug delivery. Various methods employed in phytosomal preparation and characterization along with the phytosomal advantages over conventional herbal extracts is described in the present review. The prospectus of phytosome technique can suggest new directions and endless frontier as novel drug regimen.